German: Autoimmunthyreopathie
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Definition
The term Autoimmune Thyroiditis refers to a class of chronic inflammatory diseases of the thyroid gland that are mediated via specifical antibodies or T-Cells.
Clinical manifestations
Depending on genetical factors and the pattern of circulating antibodies thyroiditis may be associated with hypothyroidism, hyperthyroidism, goiter or thyroid atrophy.
Classification
- Type 1: Euthyroidism
- Type 1A: Goiter present (Hashimoto's Disease)
- Type 1B: Goiter absent (Ord's Disease)
- Type 2: Hypothyroidism
- Type 2A: Goiter present (Hashimoto's Disease)
- Type 2B: Goiter absent (Ord's Disease)
- Type 3: Graves' Disease):
- Type 3A: Hyperthyroidism
- Type 3B: Euthyroidism
- Type 3C: Hypothyroidism
The association of Graves' disease (or other forms of thyrotoxic autoimmune thyroiditis) with TSH dependent functioning nodules is referred to as Marine-Lenhart Syndrome.
Treatment
The choice of treatment depends on the underlying disease and clinical symptoms.
References
Davies TF, Ord-Hashimoto's disease: renaming a common disorder--again. Thyroid. 2003 Dec;13(12):1189
